.
Hi.
There are numerous DAs available these days. Has anyone ever been prescribed Cabergoline (Cabaser/Dostinex)? How was your experience? What are you taking now?
Ray.
.
Hi Ray
I'm not on any medication yet but interestingly a year before I was diagnosed with PD, my mind was working overtime composing songs and poems which seemed to come from no-where so I guess the poetic 'thing' is a PD symptom and the medication probably exacerbates it.
I'm not on any medication yet but interestingly a year before I was diagnosed with PD, my mind was working overtime composing songs and poems which seemed to come from no-where so I guess the poetic 'thing' is a PD symptom and the medication probably exacerbates it.
.
That's interesting Renee.
My own efforts have all gone on investigating the side effects of PD drugs, rather than the symptoms of the condition itself, but your hypothesis seems quite likely.
Ray.
.
That's interesting Renee.
My own efforts have all gone on investigating the side effects of PD drugs, rather than the symptoms of the condition itself, but your hypothesis seems quite likely.
Ray.
.
Many thanks to PURP-SLURPS for the contribution in "Dopamine agonist threads" under "About the forum". Very succinctly put.
Hi Renee
i am very interested in your metromania (ie mania for poety, nothing to do with the undergound
).
most of the theory suggests that it is due to excessive dopamine, and so related to treatment and not the disease, the latter being a lack of dopamine. perhaps it is to do with the relative amount of dopamine between different parts of the brain, so that a lack can trigger it in the same way as a surplus?
in your case did it stop with medication or increase?
regards
i am very interested in your metromania (ie mania for poety, nothing to do with the undergound
).most of the theory suggests that it is due to excessive dopamine, and so related to treatment and not the disease, the latter being a lack of dopamine. perhaps it is to do with the relative amount of dopamine between different parts of the brain, so that a lack can trigger it in the same way as a surplus?
in your case did it stop with medication or increase?
regards
Hi Turnip
the strange thing is that I am not on any PD medication yet! I've been on Amitriptyline for 5 years for insomnia but thats an anti-depressant so not really a PD drug. Its very peculiar but I'd be sitting at my desk at work and just had the urge to type little poems and stories. Very Strange
the strange thing is that I am not on any PD medication yet! I've been on Amitriptyline for 5 years for insomnia but thats an anti-depressant so not really a PD drug. Its very peculiar but I'd be sitting at my desk at work and just had the urge to type little poems and stories. Very Strange
hi Renee
that is interesting. most perplexing.
as i have recently found, even something as innocuous as 'poetry' can be quite unpleasant if the obsession gets carried away with itself. of course the effects are negligible compared with gambling etc.
there was an interesting article where people who had deep brain stimulation treatment all lost that creative urge. most of them missed it.
but as i like to remind folk, the disease and drugs trigger 'creativity' but they don't increase talent! if only they did! its more fun doing it than receiving it and the poem or whatever always appears much better as its being done than in the cold light of the next day. but anything that is 'fun' can turned into a compulsion and then it isnt much fun. unfortunately for the rest of the world, there is also the urge to share it. thankfully there is appropriate places on the forum where this can be done safely.
(before i get into trouble, i'd better point out that there are several people with genuine talent that post but i wont name them as i might miss someone.)
cheers
that is interesting. most perplexing.
as i have recently found, even something as innocuous as 'poetry' can be quite unpleasant if the obsession gets carried away with itself. of course the effects are negligible compared with gambling etc.
there was an interesting article where people who had deep brain stimulation treatment all lost that creative urge. most of them missed it.
but as i like to remind folk, the disease and drugs trigger 'creativity' but they don't increase talent! if only they did! its more fun doing it than receiving it and the poem or whatever always appears much better as its being done than in the cold light of the next day. but anything that is 'fun' can turned into a compulsion and then it isnt much fun. unfortunately for the rest of the world, there is also the urge to share it. thankfully there is appropriate places on the forum where this can be done safely.
(before i get into trouble, i'd better point out that there are several people with genuine talent that post but i wont name them as i might miss someone.)
cheers
.
Hi all.
Can we steer this thread back to its original topic: whether people should be warned about the possible OCD side effects of certain PD drugs - predominantly Dopamine Agonists.
The main objection to warning people seems to be that we don't want to unnecessarily scare them away from what are otherwise VERY effective PD drugs, when 76% of them will experience no OCD ill effects whatsoever.
On the other hand, without warnings 24% of recipients will unwittingly slide into OCD madness, which at its worst we know can destroy marriages, families, careers and lives. On this forum alone we have become aware of scores of sufferers who have literally lost millions and gone bankrupt, ended up as vagrants and in some cases caused the deaths of loved ones or ended up in asylums. Worldwide we know there are thousands still in this state.
So, do we cause 76% to miss out on the undoubted benefits of some otherwise excellent drugs?
Or, do we probably save the lives of the other 24%?
.
Hi all.
Can we steer this thread back to its original topic: whether people should be warned about the possible OCD side effects of certain PD drugs - predominantly Dopamine Agonists.
The main objection to warning people seems to be that we don't want to unnecessarily scare them away from what are otherwise VERY effective PD drugs, when 76% of them will experience no OCD ill effects whatsoever.
On the other hand, without warnings 24% of recipients will unwittingly slide into OCD madness, which at its worst we know can destroy marriages, families, careers and lives. On this forum alone we have become aware of scores of sufferers who have literally lost millions and gone bankrupt, ended up as vagrants and in some cases caused the deaths of loved ones or ended up in asylums. Worldwide we know there are thousands still in this state.
So, do we cause 76% to miss out on the undoubted benefits of some otherwise excellent drugs?
Or, do we probably save the lives of the other 24%?
.
I think there are far more people suffering side effects from DA's than anyone knows but all the time they are helping people that is the priority. If the adverse side effects were physical there is no way in a million years these drugs would be still available.
Hi Ray,
anwser to your two questions
if the other 76% have the undoubled benefits of some da,then i would say please take heed of all the infor and advice and consider carefully before embarking on this course of treatment for them selves but it is your choice but leading to your 2nd question.
yo,re not but saving the lives of the other 24% but also many more ,that i mean,o/h,family and friends and people who care for this person who are on the da,s
anwser to your two questions
if the other 76% have the undoubled benefits of some da,then i would say please take heed of all the infor and advice and consider carefully before embarking on this course of treatment for them selves but it is your choice but leading to your 2nd question.
yo,re not but saving the lives of the other 24% but also many more ,that i mean,o/h,family and friends and people who care for this person who are on the da,s
.
Hi.
That's a very good point.
If every DA/OCD sufferer were to unwittingly drag three dependents down with them (e.g. spouse & kids), then for every 100 DA takers you could end up with:-
Patients gaining all of the undoubted benefits of DAs, with no OCD side effects: 76
People whose lives could potentially be catastrophically destroyed by OCDs: 96
If we were to extrapolate this hypothesis to the whole of the UK, which has 120,000 Parkinson's sufferers, we'd end up with 115,200 innocent people destroyed as opposed to only 91,200 happy customers.
Ray.
.
Hi.
That's a very good point.
If every DA/OCD sufferer were to unwittingly drag three dependents down with them (e.g. spouse & kids), then for every 100 DA takers you could end up with:-
Patients gaining all of the undoubted benefits of DAs, with no OCD side effects: 76
People whose lives could potentially be catastrophically destroyed by OCDs: 96
If we were to extrapolate this hypothesis to the whole of the UK, which has 120,000 Parkinson's sufferers, we'd end up with 115,200 innocent people destroyed as opposed to only 91,200 happy customers.
Ray.
.
Goodness ray....where did that all come from....LOL
Glenchass
Glenchass
In one of the other threads we found info about use of nicotine patches in treating Parkinson's in a French hospitalwith great results.
It sounds too good to be true but has anyone in the forum tried it?
Any ideas?
Have you tried it Ray?
It sounds too good to be true but has anyone in the forum tried it?
Any ideas?
Have you tried it Ray?
No, I'm afraid not. Sounds interesting though.
I wonder if Kate will know anything when she next logs on?
R.
I wonder if Kate will know anything when she next logs on?
R.
Hi Ray
I found this in treatments thread under Levadopa and followed the instruction to Google it....wonder if it's just internet rubbish or real stuff? This came after discussion of nicotine and explains where to find all the info...
Posted - 25 Jan 2011 12:49
Report this post
Google - Gabriel VILLAFANE Hôpital Henri Mondor – Créteil
He has been treating PD sufferers with Nicotine Patches for 8 or 9 years.
There is currently a clinical trial underway in France.
Apparently it assists in the formation of dopamine, making your medication more effective
I found this in treatments thread under Levadopa and followed the instruction to Google it....wonder if it's just internet rubbish or real stuff? This came after discussion of nicotine and explains where to find all the info...
Posted - 25 Jan 2011 12:49
Report this post
Google - Gabriel VILLAFANE Hôpital Henri Mondor – Créteil
He has been treating PD sufferers with Nicotine Patches for 8 or 9 years.
There is currently a clinical trial underway in France.
Apparently it assists in the formation of dopamine, making your medication more effective
.
I've read that nicotine can extend the positive effects of dopamine, and increase sensitivity in brain reward systems. However, nicotine is unique in that it has the ability to switch from being a sedative to a stimulant and vice versa, so I think I'll give it a miss.
There are plenty of natural sources of dopamine (e.g. bananas, including the skins), but dopamine's molecular structure renders it unable to cross the Blood Brain Barrier (BBB) and get into the brain. That's why L-Dopa drugs like Sinemet contain "extras" such as Carbidopa to hopefully resolve this problem.
R.
.
I've read that nicotine can extend the positive effects of dopamine, and increase sensitivity in brain reward systems. However, nicotine is unique in that it has the ability to switch from being a sedative to a stimulant and vice versa, so I think I'll give it a miss.
There are plenty of natural sources of dopamine (e.g. bananas, including the skins), but dopamine's molecular structure renders it unable to cross the Blood Brain Barrier (BBB) and get into the brain. That's why L-Dopa drugs like Sinemet contain "extras" such as Carbidopa to hopefully resolve this problem.
R.
.
I posted the references to nicotine patches in response to a request for possible alternatives when one's current meds efficacy declines. I was not advising their use simply pointing out that there are clinical trials currently underway in France.
The doctors involved are in the process of patenting their patches specifically for PD treatment
Link to French PD news
http://www.mondefrancoparkinson.com/pages/informations3.html
Link to initial findings
http://www.sna.org.ar/pdf/publicacion/vol_27_2002/n2/v27n2_p95_97.pdf
There was some discussion on this on another forum, sparked off by a French PDer starting this nicotine patch treatment in France. Some guys in the USA had tried it for 2 years or more, but not at the levels stipulated by the French Neuro.
As always, there are conflicting opinions and trial results on the neuro-protecive effects of Nicotine.
The doctors involved are in the process of patenting their patches specifically for PD treatment
Link to French PD news
http://www.mondefrancoparkinson.com/pages/informations3.html
Link to initial findings
http://www.sna.org.ar/pdf/publicacion/vol_27_2002/n2/v27n2_p95_97.pdf
There was some discussion on this on another forum, sparked off by a French PDer starting this nicotine patch treatment in France. Some guys in the USA had tried it for 2 years or more, but not at the levels stipulated by the French Neuro.
As always, there are conflicting opinions and trial results on the neuro-protecive effects of Nicotine.
Hi all.
This Scottish legal case may be of interest.
http://www.bbc.co.uk/news/uk-scotland-glasgow-west-12356147
Ray.
.
This Scottish legal case may be of interest.
http://www.bbc.co.uk/news/uk-scotland-glasgow-west-12356147
Ray.
.
IS IT ME IS IS IT OTHERS OR IS IT DRUGS
Are you ok, Ali?
