Drug Trial to Counteract Dopamine Agonist Compulsive Behaviour

Just got this off the Michael J Fox website. Thought it may interest a few people here. Maybe there is a light at the end of the tunnel for those of us who cannot take DAs due to compulsive behaviour side effects!

Daniel Weintraub, MD, of the University of Pennsylvania will conduct the first placebo-controlled trial of an agent to treat impulse control disorders associated with certain Parkinson’s disease treatments known as dopamine agonists. Naltrexone, which blocks opioid receptors, is approved by the U.S. Food and Drug Administration (FDA) for the treatment of alcohol dependence and has shown benefit for pathological gambling; it has also been shown to be safe and well-tolerated in people with PD. In this three-year study, Dr. Weintraub will explore its safety and efficacy against impulse control disorders in 48 Parkinson’s patients diagnosed with one or more impulse control disorders that developed in the context of dopamine agonist treatment.
Hi Andyned

Thanks for this information. I shall look out for any developments.

I'm a bit wary though of taking meds to counter other meds for our condition. Each drug brings its own problems.