Hi Gus I'm not on Sinimet I take Madopar I know they are both L-dopa.
Because I sleep really badly I don't wake up to take my meds I take them when I wake up naturally so for instance today woke up at 5am stayed in bed trying to get back to sleep till 6.30 failed so took first dosage then and they are Madopar dispersible x 3 @ 62.5 mg 1 x entacapone @ 200 mg 2 tablets of Ropinirole to make dosage up to 6 mg so 1 x 2 mg and 1 x 4 mg ( they do not do a 6 mg pill ) 1 x trihexyphenidyl @ 2 mg and the latest addition 1 x Amantadine @ 100 mg.
Then I time the next dosage from there by exactly 4 hrs so again to day at 10,30, 2.30, and 6.20.
With the Madopar they are taken as a 3 x 2 per day and a 2 x 2 per day.
About an hour later I eat then and take the other 20 for my blood pressure and everything else.
This seems to work well for me at moment as in the last three weeks I have only had 3 distonia attacks.
And my tremor has never been so well under control.