Hi there I hope someone can help me, I have been taking Sinimet for about a year and it has helped the pain in my shoulder however over the last 2 months I have a flem cough and integestion I have a bloating feeling as well could it be the results of the sinimet now kicking in?Any advice would be good I have tried taking them with milk and have been taking Omprazole 20 mg.
Hi Diesel dog
Taking Sinemet with any form of protein (i.e.milk) is a bad idea. It severely restricts the efficiency of the Levodopa/Carbidopa medication. Try taking it with fizzy soda.
Thanks Pokermid I will try this I have also had a thought could this be a Ulser I will be going to the doctors tomorrow to check it out.
I’m currently on 2 50mg tablets 3 x per day my PD nurse has suggested up the dose slowly to 3 tablets 3 x a day.
Does anyone on here know what a high dose of Sinimet would be? Just thinking increasing dose means there’s less room to increase in the future.
Thank you for your comment JD2024 and we hope this community is helpful. This webpage on Parkinson’s medication might be helpful - Parkinson's drugs | Parkinson's UK - but we would recommend asking your GP or Parkinson’s nurse for more information and advice as well.
Should you need it, e also have a helpline where we can put you in touch with one of our Parkinson’s nurses who can offer their advice and guidance. It’s free and confidential and can be reached on 0808 800 0303.
Parkinson’s UK Moderation Team 
Hi Diesel_Dog, Ivebeen taking Sinimet for about 14 years. DO NOT TAKE THEM WITH ANYTHING THAT HAS PROTEIN IN IT. Read the last line again, its so important. They either wont work or will stop working and eating anything high in protein will stop them working and it’ll hit you like a sledgehammer. The ‘side effects’ are very bad, for me anyway. I am supposed to take 1 x 25/100 & 1 x 12.5/50 every 3 hours. No chance! I can get through 3-4 days worth in a single day. When you take them, take them with water. I suspect that the phlegm is in fact to do with the fact that you’re taking them with milk. I know it’s difficult but try and avoid foods high in protein, like fish. Eat a nice piece of salmon and you’ll come fron an on period to an off period with a bang. This is where my little blue pals used to help but after my second hospital trip, they took them off me again (Ongentys, or Opicapone). They would ease the transition from an ON to an OFF period. Unfortunately one of the side effects is to, pardon my crudeness, increase your sex drive. When I looked into it, I found they were originally used for Erectile Disfunction. Seriously though, what colour is the phlegm, is it frothy or clear like water? I suspect it’s Acid Reflux! Anyhow, I take every day as it comes. By the way, if it is phlegm, you should - apologies in advance - always swallow it. I could be wrong but I think in the Ilium in the small intestine are things called Paers Glands (apologies for the spelling). These pickup the bacteria causing the infection, create antibodies and send them to the lungs to fight the infection. Besides this, you should always examine anything your body excretes, it is your body giving you clues.
Dave.