My question is, is it normal to take Anti de presents with PK meds or can you manage without them.

I have been given Sertraline AD but seem to make me worse, do i need to persevere or come off them.

I only started a week ago but I feel so much worse now I'm taking meds than I did befire i was diagnosed.

Starting on meds can be very difficult. We all seeem to react differently. I would think that a week is not long to give it, unless you are having nasty side effects. Which drug are you taking? Is the dose still increasing?
Sorry, just seen that you said sertraline-- it's the middle of the night-- I don't know that one.