So, I said I would report my observations in the changes in my PD progression over the 7 months I have been taking Ambroxol, and here is the list and approximately when I observed them:
Reduced brain fog and improved mental clarity 2 months
Reduced PD related shoulder pain 2 months
Improved motor function, left hand in particular 3-4 months
Reduced freezing episodes, more easily broken 6-7 months
PD facial mask thawing somewhat 6-7 months
Eliminated Requip medication for movement 7 months*
Improved mental control over my tremor 7 months
*very important for me given its side effects of obsessive & compulsive behavior and an exaggerated reality toward hallucinations
What am I still looking for?
Further movement improvement and in particular speed & gait
Tremor reduction **
** I have stopped taking Propanalol for tremor as it was making my ankles swell, symptomatic of heart issues, since then my ankles look like mine again, but my left hand tremor is back and takes quite a lot of mental control to stop, but I can do it (7 months)
So if I conclude I am not beyond the point of no return, beyond which no amount of medication or therapy will much improve my condition, then just how far can Ambroxol take me back to my pre PD normal? That is the question. I have upped my dosage to 900 mg a day at 7 months, but not as consistently as I would like to say much about it. Fairly soon I plan to go all the way up to the 1,100 mg a day trial max dose to see if that breaks through some of the remaining progressive symptoms over time. I will continue to report my progress or lack thereof going forward as always.
You know, aside from Ambroxol’s use for dry cough, sore throat & now its potential role in treating PD, it has also been found to have uroprotective effects and helps manage the pain of Fibromyalgia nerve pain, IBS & bladder pain, as well as when topically applied chronic regional pain (all these have published research around them). But I have to say even I was somewhat astonished today to find this recent patent application for an Ambroxol use, but since the plant from which it is derived has been known for its multi facteted medicinal properties for over I believe 2,000 years, I guess I should not be all that surprised, but perhaps you will be:
US Patent Application for AMBROXOL TO IMPROVE AND/OR EXTEND HEALTHSPAN, LIFESPAN AND/OR MENTAL ACUITY Patent Application (Application #20200215089 issued July 9, 2020)
Apparently they have research in mice that backs up their claim cited in this application:
So I end up wondering just what can’t Ambroxol do or at least help???