Different medication and Dyskinesia

Hello all, I’d like some advice if possible. I’ve been diagnosed for 4.5 years and until recently was fairly stable and doing ok. I’m on 6 x Stalevo a day 175 mg first thing followed by 5 x 125 mg through day. Recently been getting bad wearing off after 2 hours with whole body cramping and severe dyskinesia. Usually like this for approximately one hour until next dose. I
Spoke to Parkinson nurse and consultant who suggested I come off Stalevo and go on cocareldopa with Opicapone at night. I’ve done this and am still getting cramps / dyskinesia. How long should I give the new drugs regime to fully work? Anybody experienced anything similar? Appreciate any help / advice.