Hi Kittens & Moonandstars,
I was given Pramipexole(Mirapexin, a dopamine agonist similar to Requip). As I was concerned about the side effects I started on a very low dose, titrating really slowly over a several months, nothing happened (no trouble with side effects either) until I reached the maximum dose . This took at least six months . After a couple of weeks on this top dose I noticed I felt much better in every respect and it continued to reach a very satisfactory level; less pain, less stifness and cramps, better mood, better writing, fewer shaking moments, more self confident because of better movement .I stayed on this for almost 5 years. The only thing I would do different now with hindsight is that I would titrate in stages, i.e. increase to several levels(like you do in deep sea diving) pausing at several stages to let the effect of the drug sink in, and then after a while continue titrating upwards if no benefit was felt.
So I would say: be patient and if you do not feel it helps to relieve bothersome symptoms contact your neuro consultant or nurse asking them if an increase in dose could be the answer.