GDNF - Where are we?

Could someone from PUK please tell me what the up-to-date situation is with GDNF?

Even if it’s just a link or whatever. I was just looking thru the PUK ‘Drug Treatments for Parkinsons’ book, and noticed that PUK had funded the GDNF trial, so it would be good if someone from the organisation could give me the definitive information.

Many thanks.

Hi GoJo,

We’ve got lots of information on the GDNF clinical trials on our website, which you can find here:

We’ve also put together a detailed blog post explaining the results of the trial:

And a Q&A blog post answering questions from the public on the trials, their results, and the hope for the future:

Hope this helps. Please do let us know if you have any more queries we can help you with.

Best wishes,

Moderation Team

Great, thanks Owen. I’ve read those and learned.

However, I’d like to know if there is any ongoing work on GDNF anywhere. It seems like such a promising avenue, and I hate to think no one has picked up the baton.

Is Parkinson’s UK not involved in taking GDNF forward? If not, is someone? What about the Michael J Fox Foundation?

Hi @GoJo,

To answer your question about our involvement, we’re excited about the future of GDNF as a treatment for Parkinson’s and we’re fully committed to exploring the potential it could hold. We’re currently working with the scientific team, companies, charities and patients to explore possible routes to further studies.

If you have any questions about GDNF you can call our helpline on 0808 800 0303 or email [email protected]. Our helpline is open Monday-Friday 9am-7pm and Saturday 10am-2pm.

Best wishes,

Thanks Reah, I’ll call the helpline soon.

1 Like

You’re welcome @GoJo. :slightly_smiling_face:

to see if GDNF actually works follow this link ;

This will take you to a website set up by the phase 2 GDNF trial participants whose view is that GDNF works its just the scientists who haven’t proven it yet.