I'm interested in the pesticides too, as one of the things that trigger the inflammation causing PD.
They can work with/cause synergistic damage with another chemical, lipopolysaccharides (LPS, or endotoxin) that's made by some kinds of bacteria.
In the horrible experiments they do to "model" PD, they put one dose of lipopolysaccaride into the brains of animals. It triggers inflammation that is self perpetuating, like a slow smouldering fire, in the same types of cells and the same areas of the brain as in parkinson's, and causes progressive disabilities in the animal that are similar to parkinson's.
Lipopolysaccharide is made in the walls of gram negative bacteria, like salmonella and the one that causes meningococcal meningitis. (Most bacteria we have in us, or get infected by, don't make LPS)
I've not come across anything saying that having salmonella infection in the digestive system is a risk for parkinsons. I think it's a problem when you get it into your bloodstream, and if it then crosses into the fluid that's around the brain.
There was a researcher who got accidentally injected with LPS from Salmonella and she got parkinsonism from this. I think she's called Ines Niehaus. She's carried on doing research and has been writing about LPS and PD.
The thing about head injury and risk of PD is interesting. Head injury, LPS and pesticides are three of the things that can make the barrier between the blood and the fluid round the brain more permeable.
I think LPS can also be produced by some bacteria inside us if we get the wrong bugs growing too well in our digestive system, and then the gut wall gets more permeable.
There's researchers saying that having overgrowth of bad bugs in our digestive tract is one cause of parkinsons.
Pesticides are one of the many things that can help mess up your immune system so that you get the wrong bugs growing in your digestive system.
and pesticides work with LPS to trigger that self perpetuating inflammation in the parts of the brain involved in parkinsons.
I agree with what several people here said - that this is like with the tobacco companies.
Maybe it's worse in some ways. It's always been much the same companies that make pesticides and pharmaceuticals.
And even where it's not been the same individual company selling us both the harm and the medicine, it's the same people and organisations who have their money invested in all these companies.
I think these things work against us getting answers and the changes we need to prevent harm to others in the future.
1) The funding and publishing of research into both the safety of pesticides,
2) The funding decisions and publishing of research into the causes and treatment of PD.
3) which treatments and what information ever reach the NHS, their approved charities, and our doctors
4) the political decisions taken on regulation of pesticide use,
are all influenced by the money these companies have, their lobbying power, and our political system that allows our MPs and unelected Lords n Ladies to directly personally profit from these companies doing well.
Could make you feel hopeless on a bad day. Just have to keep self educatin, as much as we can
my cognitive ability and use of words is gone a bit downhill - if anyone comes across sites looking at this kind of stuff, and translating the science into plain words, I'd be really glad if you could post them up here