An interesting input from you.
The question of a hereditary link with PD is, as I understand it, still being researched and the thinking is that some forms of the disease may have a hereditary element, particularly early onset.
I was diagnosed with PD six years ago at the age of 73. There has been a significant deterioration in my condition since then but I’m still fighting and my cognitive skills are still good.
My sister was diagnosed with PD (aged 58) fifteen years ago. Her deterioration has been a lot slower. Neither of my parents had PD as far as is known, but two maternal aunts had PD, albeit in very old age.
My identical twin brother (so dear to me) died suddenly two years ago, after a massive bleed to the brain caused by CAA, a disease caused by rogue proteins softening and weakening brain tissue. PD as I understand it, is rogue protein related but has absolutely no link to CAA.
One link I have been questioned about (I’m a volunteer for a study group) is contact with crop sprays. Me and my siblings were brought up in a very rural environment where crop spraying was common and there was then, no legislation or control. Maybe there is a link especially to the developing brain of childhood and youth.
No chance of me having DBS because of my age - 80 next. My PD consultant wants me to go on Tolcapone, three times a day in addition to over thousand mg of Madopar but I am not happy about it, because of the possibility of liver damage associated with Tolcapone. On the guide notes that come with the medicine it also states, ‘do not take if you have symptoms of severe muscle stiffening". I’m trying to find out if that includes dystonia, which I have often and is very painful.