Hello There


#1
Dear All

I am a 61 year old male living with my wife and 26 year old son in Edinburgh. We also have a 30 year old daughter, currently on a two year adventure in New Zealand. I developed a right leg tremor around June 2009. In January 2010 I was seen by a neurologist who asked for a head MRI scan and a DATscan. The MRI was negative and the radiologist (a professor) reported the DATscan as negative also. By the summer of 2010 I had developed a right hand tremor too, occasionally with a tremor in the left foot. The neurologist referred me to one of his colleagues for a second opinion, who on seeing me in January of this year, advised that I had Parkinson's. He disagreed with the radiologist about my DATscan, indicating that there was a hint of loss in the dopamine region (around the tails of the two coma-shaped regions iin the middle of the brain). We agreed to postpone medication. He saw me again in July this year and advised that I take beta blockers (propranolol) in the first instance if the right hand tremor continues to increase. The tremors increased, especially when nervous. Hence, I took propralnolol for about three months this summer but to no avail. Through an email exchange he advised me to stop the propranolol and start sinemet which I started taking on Tuesday, beginning at 1 tablet twice a day (to increase gradually over four weeks to the full dose of 2 tablets 3 times a day). So far the sinemet has had no effect whatsoever (I know it is only 4 days since I started, but I thought I might feel some improvement, no matter how small). All along since the beginning of my tremors 2.5 years ago I have continued playing racket ball and badminton weekly (as I have been doing for three decades) running around the courts without any problem. Do I really have Parkinson's or is it some form of essential tremor? Will taking the full dose of sinemet be detrimental if I do not have Parkinson's? Answers to these questions will probably arise in the next few months. Mean time I will be interested in anyone's thoughts out there. Have a nice weekend all

#2
Hi Janig welcome
I was dx last year age 47 my MIR scan was negative but my neuro said this was what he expected
He told me that dopamine does not show on a scan
It really takes a while to adjust to the meds and which work for you
Well Done for playing badminton /ect
I go to a pilates class swim and gym a bit This really keeps going
Regard Adian

#3
Thanks Adrian and real good to hear from you.

Actually the dopamine region lights up in an expensive test called DATscan,, which involves injection with a harmless radioactive agent that binds to the dopamine region over a period of three or so hours,following which a scan is carried out. It is well documented that by the symptoms arise about 80% of the region is depleted, yet mine was the reverse (more than 80% was still there) which makes me wonder how accurate my PD diagnosis is. Mind you if I do have PD I will just get on with it and make the most of life as usual :smile:, Let's see how I respond to sinemet 62.5 which, as I said earlier, I would be on two tablets 3 times a day by Christmas.

Cheers