Madopar Side Effects


I was diagnosed with mild Parkinson’s on 17/9/18. I was prescribed Madopar (Levadopa 12.5mgs with 50mgs Benserazide 1 capsule 3 times a day). This seemed to work well and I felt better with milder symptoms. I was told that after 2 weeks I was to take a double dose and given a prescription for this (Co-beneldopa 25 mgs/100mgs). I took one capsule and within an hour my ribcage was really taut and rigid and my walking was dreadful. These effects were part of my original symptoms but they were worse. I phoned my GP who said to leave it for a week and only take the low dosage. However she said then take another high dose capsule. She would write to the consultant to get some advice. I spoke to a Parkinsons Nurse who advised me not to take another high dose capsule as it could make me very unwell and that is the route I am going down. I cannot get to speak to the consultant to get my medication sorted and wondered if anyone else has had similar problems and what they did about it.


Hi @Chrispy27,

A warm welcome to the forum.

I’m really sorry to hear that you’ve experienced some issues with your medication. It’s a shame that you won’t be able to speak to your consultant for some time, however, if you call our helpline team, one of our advisers can arrange for a Parkinson’s nurse to call you back within 24 hours.

Please give them a call on 0808 800 0303 as soon as you can so you can get additional support on this.

Best wishes,