neupro,european dosing


#1

my neuro here in the u.s. has me on ‘European’ dosing. the fda here indicates 8mg/day is the max dose for parkinsons. my insurance has approved an increased dose. does anyone know the max daily dose approved in England?


#2

See,

https://bnf.nice.org.uk/drug/rotigotine.html

For the generic, rotigotine patches, used for Parkinson’s the recommendations are:

  • 8mg if used as a monotherapy;
  • 16mg if used with L/C.

I find the increased maximum when taken with L/C counter-intuitive. Perhaps it is suggesting that before you go to large doses you would be better to look at the efficacy of L/C for you.

The levodopa equivalent dose factor for rotigotine is 30 (i.e. roughly speaking 1mg of rotigotine gives the same benefit as 30mg of levodopa).

John


#3

Hi Cathyj
Do you know what medication you are on as I am on ropinirole and I can go up to 24 mg a day hope that helps
Lee