Nilotinib made a big splash a few years back and now some results are available.
Maybe not what was hoped for, but still some cause for hope.
But as usual, there seems to be expressions of caution and need for more research, meanwhile my disease progresses, my life deteriorates, and hope slips away. So much more important to do more research. hhmmmm

Hi Jakarta,

We are aware of Nilotinib and have written a recent blog and news article about the latest trial results published last month. Your post is accurate in that the recent results were ‘not what was hoped for, but still some cause for hope’ and we can understand the frustrations of those that have Parkinson’s.

I hope you find this information helpful.

Best wishes,

I have felt this way too. But I think it’s important for us to retain hope, and avoid cynicism.

Does anyone know the CSF concentration nilotonib reached along with the IC50 value? Did it reach the required concentration in the brain to inhibit c-abl