http://www.eurekalert.org/pub_releases/2013-05/gumc-cdp050313.php
This compound is in use for the treatment of leukemia so all its toxicity data is well known. It can go straight into phase 2 clinical trials for PD.........
sounds very promising....but as always we shall have to wait and see.
thanks
thanks
ps you are no 7 in a google searck om recent nilotnib stories - fame at last!
headline
Nilotinib [u]reverses[/u] loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models
http://hmg.oxfordjournals.org/content/early/2013/05/09/hmg.ddt192.abstract?sid=b45c60fd-bf7c-4014-a2e6-d0f133651625
Nilotinib [u]reverses[/u] loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models
http://hmg.oxfordjournals.org/content/early/2013/05/09/hmg.ddt192.abstract?sid=b45c60fd-bf7c-4014-a2e6-d0f133651625
ps translation
this drugs causes the brain's vacuum cleaners to sweep up rogue proteins which revitalises inactive neurons
this drugs causes the brain's vacuum cleaners to sweep up rogue proteins which revitalises inactive neurons
or to put it another way
IF THIS WORKS EVERY NEURO-DEGENERATIVE DISEASE STOPS GETTING WORSE AND COULD EVEN IMPROVE
of course it might not... but this just could be the big one.
IF THIS WORKS EVERY NEURO-DEGENERATIVE DISEASE STOPS GETTING WORSE AND COULD EVEN IMPROVE
of course it might not... but this just could be the big one.