I have been taking Stalevo for several years, and have had good results. Recently, my pharmacist has supplied Stanek and/or Sastravi with the same active formulation. I accept that it may be coincidental but, since this change, my PD symptoms have deteriorated significantly; where previously I was “on” until the next 3-hourly dose was due, I now turn “off” before it is due. Where previously the turn-off was gradual, now it is like throwing a switch. I also find that it can be as much as an hour after a dose before I feel the benefit.
Are these alternative products made to give identical controlled-release profiles? These effects could, of course, be due to the progression of my PD, or (for some reason I cannot imagine) be linked to hip repair surgery at about the same time, but the fact that they coincided exactly with the change of product.makes me ask the question.