Prostate cancer and Parkinsons

As well as Parkinson’s I have advanced prostate cancer for which I am about to start Chemotherapy with docetaxel. I am concerned about interactions between the drugs used to treat side effects of docetaxel and my parkinson’s medication (Co-Beneldopa and Ropinirole ).
I found some useful info on the Parkinson’s Australia site.


but would like to know of any problems encountered by someone who has been down this path?

Hi philpits,

I hope you’re well this evening. While I’m sure that the forum members will reply to your post, I also wanted to ask you if you’ve spoken with your GP or specialist about the concerns you have with your medications? They will have knowledge of these medications, as well as your condition, and are best placed to speak with you about this.

I’m going to let the team know about your post, and they will respond to you as soon as possible, but if you feel like it might be helpful, please do give our helpline a call on 0808 800 0303 to speak to a Parkinson’s advisor.

Take care,
Moderation Team.

Hi @philpits,

I hope all is well.

I would recommend you discuss this issue with your Consultant Oncologist, they have information regarding potential side effects of specific Chemotherapy drugs and any potential interactions with other drugs. Your Oncologist can discuss this with your Consultant Neurologist if needed.

I hope you find this information useful.

Best wishes,

Thanks Reah.
I am enrolling on a drug trial so am changing hospitals and consultants for my prostate cancer. The new consultant seems more knowledgeable about the drug interactions so I am feeling more confident. I am due an appointment with the Parkinson’s specialist in August so will get his take on it then.


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I have had Parkinsons Disease for 12 years and have recently been diagnosed with Prostate Cancer. The treatment offered to me for the prostate is Hormone Therapy. I am concerned about the impact this may have on my P.D. I should be very pleased to hear from anybody who has had experience of both ailments. Many thanks

Good evening Gerrard … I am 69 & had a positive Datscan nine months. I have Atypical Parkinson’s also Neuropathy & Atrial Fibrillation. Ten years ago I was diagnosed with Prostate Cancer. I was given 3 options … Prostate removal, Brachytherapy or hormone & radiotherapy. My choice was the hormone option.
So I saw a consultant who would do the hormone / radiotherapy treatment BUT because of my young age [59] she said I should have my prostate removed. Her reason being that if the cancer returned then there would be difficulty in removing my damaged prostate. So I went for the removal option & my cancer has not returned. So I probably took the right option.

Any questions please ask.

Best wishes

Hello Steve,
Thank you for your response. We seem to have followed similar paths, I have also had Neuropathy. In addition I have recently been diagnosed with Atrial Fibrillation and am currently fighting Lymphoedema in my right leg which is badly swollen and quite painful. This is dominating my mind whilst I try to figure out whether I should opt for HormoneTherapy. Prostate Cancer was diagnosed on the basis of a high PSA (229). Scans have not revealed any metastatic disease. I am aged 89 which is inclining me towards refusal

Good afternoon Gerrard … Is the age 89 a typing error ? You certainly write like a much younger man. I assume you take Amitriptyline for the Neuropathy ? I had a bad ulcer on my right heel & a swollen right foot & numb left foot. Amitriptyline cleared up the ulcer & swelling. My legs still feel not too good. It is like weighing 20 stone
[ I weigh 13 stone] & trying to walk.

That is a very high PSA score … mine went rapidly from 12 to 28 & I had a prostate biopsy [ now that was not a lot of fun, bit like having a BB gun shoved up you know where & pulling the trigger about 20 times], which showed my cancer had a score of either 5 or 10 … not sure which but it was as high as the scale went. I saw a surgeon on the Friday & had the prostate removed on the Tuesday. In hospital for 5 days & then had a catheter for a month & felt sub par for 12 months.

At age 89 watching might be the best option quality of life wise … but you should listen to medical advice of course.

I’m told all the good looking men get prostate cancer. A lot of men die with it rather than because of it.

Best of luck.

Hello again Steve.
Yes - Prostate permitting, I shall be reaching the grand old age of 90 in July. Despite having Parkinsons for the last 12 years, I have managed to maintain a youthful outlook and disposition. I was very fortunate in not experiencing any serious illness until I was diagnosed with PD in my 70’s. I recognised it for what it was as I had an older brother and sister who also suffered from it. I now seem to be collecting illnesses month by month. Having never visited a Doctor for most of my life, I now visit the surgery almost every week. When I face the Doctor, I am never quite certain which illness I should prioritise. I believe the Neuropathy has left me, It troubled me in my foot and only occurred when I was in bed, caused by the weight of the bed clothes. For reasons connected with PD, I have recently changed my bed and now sleep in a Riser/Recliner chair. This assists me to get in and out of bed which I have to do frequently at night - i had difficulty getting out of a standard bed. One of the benefits of this change has been the absence of neuropathy,… I shall spend some time considering what to do regarding the Prostate. If I were younger I would definitely accept the Hormone treatment but I don;t anticipate I have many years left and hope to spend them as trouble-free as I possibly can,

Kind Regards,