Well, depends how you look at it really. You could easily go in for conspiracy theories - PUK getting into bed with Big Pharma, BPh not wanting a cure for PD coz they'd lose a captive market, PUK not wanting a cure coz all the staff would lose their jobs (or, even simpler, just coz the only point of an organisation is to protect itself). I run a tiny charity myself and I know how easy it is to get into management-speak and forget your users.
Or - you could say, PUK making the best collaborations, stripping out the excesses of the market place, BPh desperately looking for a cure for PD coz their existing drugs are all off-patent and make them nothing at all and a cure would be huger than huge (look at how productive we'd all be), PUK doing its best coz you don't go to work for a charity for the pay, believe me, or the kudos (getting beaten up by government ministers is no joke), but mostly coz you hope you can make a difference to the human condition (usually against the odds).
But that pesky PD, (?like similar conditions) is just not that straightforward. Actually (and I'm a physicist not a biologist) it seems as complex as cancer(s) - and without cancer-charities' money progress is slower than we'd like.
So what do we do, T? I think, let's hold PUK's toes to the flames: if we're not complacent, they won't be complacent. But let's ask what we can do for . . . etc etc. It's my disease, I want to be in charge of it.
All the best