hiya i started on sinemet 3 x daily 12.5/ 50 and i had no headaches.
i was then moved uptoo 12.5/50 6 a day and for the first week i had really strong throbbing head aches, on the second week that passed.
now generic sinemet+ 25/100 4x day, no headaches.
my gp said i had headaches due too the adjustment too the dose, i do suffer from dry mouth, but i had a dry mouth(dehydration) before i started taking medication.
I dont think the generic form is as good as the lower dose of the branded sinemet, i may have gained some mobility with the duration of the pills, but i am and feel just as unsteady on my feet, aches, pains remain as does tremor and memory probs.