one last question - are the PD relevant points in colour space clustered together or strung out along the edges and if the former what are the rough co-ordinates. I appreciate you might not want to be too detailed.
Either way very interesting.
thanks
for anyone interested i think this is the same colour space http://www.optstudent.com/nucleus/index.php?itemid=72
either way it is very intersting about colour deficiencies
either way it is very intersting about colour deficiencies
Just a query that springs to mind.
I recall an experiment where lenses turning the incoming image through 180' are worn by people in the program, and their brains then readjust to the new orientation, switching things back to a sense in normality; with a similar switch in reverse when the glasses are removed.
This may be different in regard to 'colour space'; but would it be fair to say, the brain may readjust to a certain measure to compensate for the applied filters? Which will mean constant revision of prescription lenses.
I recall an experiment where lenses turning the incoming image through 180' are worn by people in the program, and their brains then readjust to the new orientation, switching things back to a sense in normality; with a similar switch in reverse when the glasses are removed.
This may be different in regard to 'colour space'; but would it be fair to say, the brain may readjust to a certain measure to compensate for the applied filters? Which will mean constant revision of prescription lenses.
Turnip - there is some clustering - but insufficient numbers to know whether the colour space positions are relevant. In other research programmes there are clusters but past experience suggests that there are a few depending on age, sex and symptoms. I'd therefore rather not give positions out at this stage.
As for image inversion being linked to colour perception - both may require changes in Rx - but it looks as though it would not be appropriate to link this.
Other longitudonal research projects suggest a very precise position in colour space is found after a year - but this has not been checked in PD (although we have found that those we have checked have been very stable).
As for image inversion being linked to colour perception - both may require changes in Rx - but it looks as though it would not be appropriate to link this.
Other longitudonal research projects suggest a very precise position in colour space is found after a year - but this has not been checked in PD (although we have found that those we have checked have been very stable).
i have been trying to find out more about light and its link to the areas of the brain most associated with pd. my rudimentary fumblings are
the retina lead primarily to the thalamus which acts like a distribution system.
the area receiving blue light electrical signals is different from the other two colour areas.
the thalamus is particularly receptive to dopamine
the thalamus is right next to the substantia nigra and basal ganglia generally
the thalamus is also involved in movement control with those adjoining areas
the thalamus is very near the areas where dbs probes are placed
so light signals, dopamine production and movement control are all to be found in roughly the same small area
ignorant speculation
blue light stimulates the thalamus
this somehow dampens down the excessive activity caused by pd
may be similar to the action of dbs
does anybody know more about this area and is able to correct my mistakes?
research - if we have questions like this how to we get answers?
the retina lead primarily to the thalamus which acts like a distribution system.
the area receiving blue light electrical signals is different from the other two colour areas.
the thalamus is particularly receptive to dopamine
the thalamus is right next to the substantia nigra and basal ganglia generally
the thalamus is also involved in movement control with those adjoining areas
the thalamus is very near the areas where dbs probes are placed
so light signals, dopamine production and movement control are all to be found in roughly the same small area
ignorant speculation
blue light stimulates the thalamus
this somehow dampens down the excessive activity caused by pd
may be similar to the action of dbs
does anybody know more about this area and is able to correct my mistakes?
research - if we have questions like this how to we get answers?
Im not really able to understand this too well but hope that you get the chance to demonstrate your results to a wider PD audience as it sounds very promising to me.
The lateral geniculate nucleus in the thalmus is affected by the signals from blue / yellow - excites / inhibits respomnses to edges / flicker. This is an area I am particularly interested in as it has been implicated in many responses - particulary the dorsal stream - the stream that is believed to control "the where is it" and direct movement. We also have recently completed a clinical trial which suggests it may be implicated in other medical conditions (sorry - not at liberty to explain at this stage).
There are other effects of colour in the thalmus too - but thats another story.
I suspect that you are getting warm Turnip! But there are other effects that need to be taken into account too - inhibition or lack of excitation - which is more important? Synesthetic and sensory integrative effects - some are so fascinating (not PD related) that they would make the most amazing documentary you have ever seen.
There are other effects of colour in the thalmus too - but thats another story.
I suspect that you are getting warm Turnip! But there are other effects that need to be taken into account too - inhibition or lack of excitation - which is more important? Synesthetic and sensory integrative effects - some are so fascinating (not PD related) that they would make the most amazing documentary you have ever seen.
As my work has not been clinically trialled in PD it would be inappropriate to suggest that I have atreatment that works at this time. But, it does need to be discussd and therefore I would be happy to show what we do at one PD conference if asked - it would take around an hour to explain - show videos etc.
I am sure would it would fascinate and stimulate discussion - but it would have to be an appropriate conference. (I am a well known and in demand speaker in my own field)
I am sure would it would fascinate and stimulate discussion - but it would have to be an appropriate conference. (I am a well known and in demand speaker in my own field)
its been an honour and a pleasure chatting with you professor B, i have had so many naive ideas removed and much more interesting ones take their place.
i read somewhere that frogs only see things when the thing moves- is the blue channel a descendant of the older brain and the other colour channels a later evolution? so that it is more closely linked with 'automatic' movement as opposed to considered movement.
i find my automatic movements (catching falling objects for example) to be quicker than ever and considered movements slower. if the former has a direct route between the retina and movement centres that might be expected. the filters remove information not add it - so how does the lack of red, green signals enhance the blue one (or whatever colour is not filtered out).
i look forward to the documentary to find out.
thanks again
(btwruvpupawue? no need to reply)
i read somewhere that frogs only see things when the thing moves- is the blue channel a descendant of the older brain and the other colour channels a later evolution? so that it is more closely linked with 'automatic' movement as opposed to considered movement.
i find my automatic movements (catching falling objects for example) to be quicker than ever and considered movements slower. if the former has a direct route between the retina and movement centres that might be expected. the filters remove information not add it - so how does the lack of red, green signals enhance the blue one (or whatever colour is not filtered out).
i look forward to the documentary to find out.
thanks again
(btwruvpupawue? no need to reply)
This is a really interesting thread. I am very much a layman with most of what I read but can I pass my experience with living with myhusband of 53 years .He has been a literate man he was an information / press officer who wrote for a living . Might I say always with very small handwriting not always legible lol..
This might not be on the same wavelength . I have always teased by telling him he was mechanically dyslexic . When a boy his father would say "OUR JOHN IS HOPELESS "
Whatever he put his hand to ended up in pieces he just could not see how to do things . Could not read a map would get everything back to front sea / lan He could play darts and ball games obviously with a lot of other things .But gradually over the years this change.
I started to become uncomfortable when he was driving (SPACIAL AWARENESS ) He no longer drives ..
His sight is not good as good and i think the specialist at the hospital was a bit confused by him .
I did post that I have been leaving light s on which helps .
Getting back to colour is there a way I can check how colour might affect him .
We also have a colourful patterned carpet which I believe is not good .
Sorry to have gone on for so long
This might not be on the same wavelength . I have always teased by telling him he was mechanically dyslexic . When a boy his father would say "OUR JOHN IS HOPELESS "
Whatever he put his hand to ended up in pieces he just could not see how to do things . Could not read a map would get everything back to front sea / lan He could play darts and ball games obviously with a lot of other things .But gradually over the years this change.
I started to become uncomfortable when he was driving (SPACIAL AWARENESS ) He no longer drives ..
His sight is not good as good and i think the specialist at the hospital was a bit confused by him .
I did post that I have been leaving light s on which helps .
Getting back to colour is there a way I can check how colour might affect him .
We also have a colourful patterned carpet which I believe is not good .
Sorry to have gone on for so long
johnnie
these symptoms are straightforward to address
send me which town you are in and i will recommend someone
these symptoms are straightforward to address
send me which town you are in and i will recommend someone
Newport Gwent
Chalmers opticians in Albany Rd Cardiff has the necessary instrumentation to sort your problems out
best wishes
best wishes
I had hoped thast there would be some response from professionals that may want to research this subject. Sadly, not one professional reply.
I would have thought there would have been great interest in stopping tremor in seconds, stopping dyskinesia and much more - no risk - immediate effect - virtually no cost.Symptoms stop during assessment. I think we can probably do much more than drugs - and without the side effects.
No one has asked me to speak at any conference - I have therefore come to the conclusion that nobody in the PD community cares about this intervention.
I have tried - but not even anyone who wishes to disprove claims (I would be happy with this response) - so - if the model I am using is appropriate (and it allows me to predict intervention effects very accurately) - then drugs will NEVER work fully.
Maybe in another generation......
I would have thought there would have been great interest in stopping tremor in seconds, stopping dyskinesia and much more - no risk - immediate effect - virtually no cost.Symptoms stop during assessment. I think we can probably do much more than drugs - and without the side effects.
No one has asked me to speak at any conference - I have therefore come to the conclusion that nobody in the PD community cares about this intervention.
I have tried - but not even anyone who wishes to disprove claims (I would be happy with this response) - so - if the model I am using is appropriate (and it allows me to predict intervention effects very accurately) - then drugs will NEVER work fully.
Maybe in another generation......
This is the link to a video showing the results of using tinted glasses:
http://www.youtube.com/watch?v=OrcO2oRv75I
http://www.youtube.com/watch?v=OrcO2oRv75I
Quote from the originator of the above mentioned video - others include a reference to a NY hospital using blue tinted lenses for PWP's and few years back.
"Unfortunately I cannot help you as I know of no research. More disappointingly, I have not been able to generate any interest in researching this effect despite several years of trying."
dyskinesia 4 years ago. diskinesia is the "name" of the author of video
Unfortunately, the reaction of some is simply to disbelieve what they are seeing because it does not fit with established knowledge or you might say their preconceptions depending on your point of view.
"Unfortunately I cannot help you as I know of no research. More disappointingly, I have not been able to generate any interest in researching this effect despite several years of trying."
dyskinesia 4 years ago. diskinesia is the "name" of the author of video
Unfortunately, the reaction of some is simply to disbelieve what they are seeing because it does not fit with established knowledge or you might say their preconceptions depending on your point of view.
The video is very interesting - however, the method of determining the filter was at best "poke and hope"
We now know how to "tuneout" symptoms accurately using instrumentation - the instruments we use were developed with UK governement funding - and they are the most advanced in the world. The methods we use are not understood by most clinicians - and this may be the problem - its outside of their comfort zone.
But we have already clinically trialled a similar technique on another medical condition and a UK medical school is working with us to develop a new treatment.
We now know how to "tuneout" symptoms accurately using instrumentation - the instruments we use were developed with UK governement funding - and they are the most advanced in the world. The methods we use are not understood by most clinicians - and this may be the problem - its outside of their comfort zone.
But we have already clinically trialled a similar technique on another medical condition and a UK medical school is working with us to develop a new treatment.
Oh - and we can switch symptoms on and off to order - in seconds!
I would have thought what I have said in these posts should have caused tremendous pressure for research in this area - it has not and therefore I have to withdraw and do not intend to post further as it is obviously a waste of my time.
I am happy to be emailed in future
I would have thought what I have said in these posts should have caused tremendous pressure for research in this area - it has not and therefore I have to withdraw and do not intend to post further as it is obviously a waste of my time.
I am happy to be emailed in future
This is a patients forum. Apart from interest I don't see how you will arouse interest amongst professionals unless you try another avenue as its not my impression that professionals take much interest in patients forums even 'though it is on just such forums that, for example, the damaging side effects of d.a.'s were exposed.
By the way, if a blue tint works, does it really matter if it is not high-tech
and possible expensive? Just a thought.
By the way, if a blue tint works, does it really matter if it is not high-tech
and possible expensive? Just a thought.
I found this fascinating, stuck on my Ray Bands and fell on me coccyx.