My experience is as follows:
dx following DATscan June 2011
symptoms: initially along with loss of smell, pain in left shoulder, initially thought to be frozen shoulder, later thought to be a torn rotator cuff, operation helped shoulder pain, but still left with little dexterity in left hand, left leg drag, no left arm swing.
initial medication: selegiline. effect on symptoms - nil.
medication review 2012: sinemet plus 100/25 introduced slowly over a two week period up to 3 daily. Azilect 1mg daily. effect on symptoms - excellent.
medication review 2013 - no change needed
medication review 2014 - added another sinemet plus daily and introduced madopar dispersal if needed for emergencies. Effect on symptoms - excellent, madopar on rare occasions when needed has been great.
im due a review shortly and see no need to alter the medications I take at the moment. I know if I eat too much protein, take my meds too close to eating or I am stressed, then my medication isn't as effective and I end up like a statue, but I normally know it's my own fault. I find if I do use madopar I have really vivid dreams that night.
would be interesting to compare experiences.