has anyone been told they have parkinsonism instead of dx of parkinsons,or been dx at first with parkinsons then treated for many years for it then had a change of dx to parkinsonism,like i have.
parkinsonism,can cause parkinsons symtoms such as slowing down,tremor,ridergty,stiffnesss,and balance problems.there are a few disorders that can produce symtoms refered to as parkinsonism,parkinsons disease is just one of them.so wots the difference?
well typical parkinsons patient has lewey bodys in the brains neurons,when a patient is givern dopamine replacement thearpy for example sinemet meds those symptoms go away.but parkinisum have typical parkinsons symptoms but does not respond to the dopamine replacement thearpy.parkinsonism has two classes.msa is a example.it produces alpa-synuclein clusters in the brain glal cells,protect the neurons in the brain,instead of in the neurons as in the case as parkinsons.involves defetive tau proteins which act as binder of microtubules of cells.a dysfunction in the tau proteins is wot causes psp and cbd.
they get grouped togeather under the catergary of parkinsonism cus they have over over lapping symtoms of typical parkinsons disease,and cus dopimine producing cells in the brain are effected in all these disorders.
psp patients have palsy,first a weakness of eye movement looking up and down,as it progresses eyes become frozern and they carnt move them in any direction,which is awful.
msa have servere automatic dysfunctions.they carnt maintain good blood presure,and suffer with urine incontinince.this is the parkinsonism i have .symtoms overlap with parkinsons disease and do not respond to dopamine meds.
i hope this information can least help some folk out there on the forum,and if you have been told its parkins,or parkinsonism,good luck to all of you