4Madapor AND Mucuna Prurines?


Madapor AND Mucuna Prurines?
Hi everyone!
Since I was diagnosed in March 2018 I have been taking controlled release 25/100 Madapor, three times a day, as advised by my neurologist, which seems to help with my tremors but doesn’t touch my stiff and aching legs. During the first few months I extensively investigated naturapathic treatments, including Velvet Bean (Macuna Prurines) - which I’ve been taking alongside the Madapor. From what I have read, macuna has much going for it. There’s a lot of published research substantiating this claim but I would especially recommend reading Dr. Rafael Gonzalez’s excellent book ‘Mucuna verses Parkinson - Treatment with Natural Levodopa’. It contains over 100 references to relevant research sources. I have been adding mucuna to my daily meds for about nine months now and feal confident it’s helping. Has anyone else tried this approach, and if so, did it help? Additionally, my naturapathic investigations suggest a number of supplements that support the remaining dopamine producing neurons as well as the importance of helping mitochondria produce ATP (energy) more efficiently. This being especially relevant to people with Parkinson’s. It’s vitally important to protect existing neurons if the progression of the disease is to be achieved (check out nootropics and mitochondrial health to see how that might be relevant to slowing or even halting the progression of the condition). This whole topic deserves more attention, don’t you think.



After reading your post I read the book, as I have been keen to try the alternative route. I am still confused with dosages to take?
I have only just started meds Madopar 125 twice a day. I would like to reduce this with MP, but am a bit wary of where to get it from and how much to take?
Also in the book it mentions green tea containing Carbidopa so would this be a good thing to take along side MP?


Hello Steph22
I’m glad you found the book interesting. It really does present a good case for trying Mucuna Prurines. I can understand your uncertainty over doseages. Many Mucuna powders and capsules don’t specify the amount of L-Dopa per dose, however the one I’m using is sold as ‘Now Dopa Mucuna’ they state that their product delivers 15% L-Dopa (120mg per dose of two capsules). I get mine from Amazon but search the web and you will find a number of suppliers. You only appear to be on a low dose of Madapar so you may find that Mucuna is a good effective substitute for Madapor. I have tried gree tea but hate the taste so by brew-ups use good old Yorkshire tea!.
Hope that helps.


Thank you
Yes it does, I will try the now one

All the best


Hello, Borg3of21,

I hope you are keeping well.

I have started the Mp along side a reduced dose of Madopar 50/12.5,
It is early days but I am planning on increasing MP and removing Madopar.
I am interested in the other supplements you mention you are taking? I am also taking turmeric and cbd oil.
Many thanks


I was prescribed Madopa and took it for 6 months during which time II felt permanently queasy and also uneasy about my body’s distaste for the drug. I also distrust the drug for the fact that it has a long list of associated “side-effects” (I call them medically-induced alternative illnesses) that are waiting to pounce in the future.So I abandoned Madopa and settled instead for Mucuna in the form of Zandopa powder. I have had no adverse reactions to this and experimented with dosage until I found one that does the job - in my case currently 20gms of powder in a little water twice per day.
I have also adopted the Auto Immune Paleo Diet on advice from a nutritional therapist in order to address chronic problems with my digestive system. I have been on it for 16 weeks now and it has done wonders. No more rumblings,bloating,constipation or diarrhea! I feel very well, optimistic about the future and I now sleep very soundly.
I like the sound of ‘Now Dopa Mucuna’ and may move towards using it eventually instead of Zandopa. Weighing out the powder is a pain and effectively rules out taking vacations away from home; but it currently has the advantage of enabling me to fine-tune my dosage. This is important because I don’t want to smother my tremor symptoms. If I do that I can’'t tell whether my other actions (like the AIP diet) are working or not. I have no aspirations of finding a cure; but my aim, which is entirely feasible, is to stop the disease’s progression and generate my own dopamine supply by natural means. Right now, I think I am winning!
I absolutely agree with you about the lack of support/attention of Mucuna. It deserves a lot more attention than the UK authorities are giving it. But it is hardly surprising, is it? I don’t suppose the pharmaceutical industry wouldn’t make any profit out of it. John


I love your expression “medically-induced alternative illnesses”. That so approprietly applies to so many conventional pharmaceutical ‘treatments’, in my opinion - especially the so-called ‘gold standard’ conventional Parkinson’s meds. My neurologist hadn’t heard of mucuna prurines, nor did he say anything regarding the benefit of taking any supplements. That I had to discover for myself. The medical profession doesn’t like it when you do this, but do it and see the bigger picture. For example; discover how PQQ (Pyrroloquinoline Quinone) improves mitochondrial efficiency and boosts energy levels. Learn the benefits of taking co-enzyme Q10, and check out what natural Astaxanthin can do to improve your overall health. There’s a dozen or so other supplements that can help ease the symptoms of Parkinson’s disease - but the medical profession seems unwilling or unable to offer any help or guideance on supplementation.

When it comes to buying mucuna prurines in powder form, I’ve discovered a UK based company (DetoxTrading) that supply a good organic mucuna prurines powder. I make up my own capsules from this powder which works well for me.

I too look to hold back the disease progression and for me that seems to be through careful supplementation. From the extensive reading I have done on the subject I even believe it’s possibe to reverse some or all of the symptoms, given time and the right supplements.

So, I say listen to the medical men but don’t be deterred from following your own path along the Parkinson’s road.


Very interesting posts.
Can you tell me how long it took for the MP to help? Was it one to two weeks?
I have been taking for almost a week and wondering if I should increase the dose yet or wait a few more days to see if the dose is right for me

Many thanks


Hi Steph22
I would say that my tremor was lessoned within about an hour of first taking mucuna prurines. I now take one capsule of MP, three times a day (plus one Madapor 25/100 three times a day) which works very well at supressing my tremors but I have to say that neither MP nor Madapor has helped improve my weak and aching legs. I have tried increasing the dose but to no avail. I still think that MP has benefits and fewer side-effects than Madapor, so I’ll see how it works in the longer term.


Hi Borg3of21

Thank you for your reply, I have ordered some powder from detox trading and plan to make capsules

They suggest 1/4 tsp a day which seems quite a high dose?
I’m hoping the MP will help to avoid increasing Madopar too soon.



Hi again Steph22
I think you are right in giving MP a go. It has many health benefits in addition to delivering L-dopa. Start on a low dose for about a week or so, then up the dose if you wish. I think the suggested dose of the MP powder from Detox Trading of a quarter of a tablespoonful should be fine. If you are making up your own capsules, that might equate to two or three ‘00’ sized capsules per dose. Alternatively you could just mix with a little water and gulp it down (it’s not too unpleasant).
From the reading I have done on MP, it seems its chief benefits stem from the very large mix of compounds present in MP, which effectively serve to avoid giving rise to side effects and any tendency to stop working, as can be the case with synthetic l-dopa. It can be taken alongside madapor, benildopa etc. So I would suggest you supplement any existing medication by adding in MP starting with a low dose at first then see how you go.
I hope it works well for you!



Thank you so much for your message. It is really helpful to hear your comments. I have read so much,that I think I am on overload. So I am going to start with a simple plan.
Thank you again for taking the time to reply