Ive added entacapone 5 months now.I was taking 7 25/100 c/l and 1 50/200 sr c/lAfter adding 1 200 mg split early two doses I cut the sinemet down to 3.5 25/100 a day with better results then before.Since the beginning I added 1 exrra 100 mg comtan with 3 rd c/l
Sideeffects seem just gas sometimes .But less constipation.Overhaul Im happier I found it .
I think people who try it start at no more than a half pill with their c/l I think even now taking 1 pill would be to much.
My myoclonus has pretty much gone away with changing from Actavis to Mylan Pharm c/l 25/100,
I am getting many reports now from others who get different results with our generic c/l.
Why I dont know but should be investigated by the FDA.