This might be the article Jean found on dropped head [antercollis/antecollis] and ropinirole:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353471/pdf/MDC3-3-91.pdf
Ropinirole-Induced Anterocollis in Parkinson’s Disease Movement Disorders - Clinical Practice Vol.3 Issue 1 L.Ameghino, M.Rossi, Á.Cammarota and M.Merello Article first published online: 13 NOV 2015
I also referenced this article in an earlier thread on this topic started by Nick: Nec drop
Snowy has also posted several times on this topic describing what he has tried:
Snowy 25d nov.21
Hi I’m in Canada originally from the UK recently diagnosed with Parkinson’s and am taking Levadopa 100/25 3× a day. I developed a headrop a few days after starting to take it
Came off levadopa Snowy Feb 7 2022
Well I came off the levadopa to see if it improved my headdrop and it was really difficult without it. My head position didn’t improve…so I have started back on it. I’m really disappointed. The only other drug I take is mirtazapine which I started originally at the same time as the levadopa. The headdrop started a few days later.
Antidepressant recommendation Snowy Mar 30 2022
Hi I wonder if anyone could let me know which ADs work for them. I take Levadopa & 15mg mirtazapine. They’re going to taper me off mirtazapine to see if it improves my head posture & stiff neck. But I don’t like the idea of the options that have been suggested (sertraline, venlafaxine, duloxetine). Would anyone be prepared to say what works for them? Thank you!
Mirtazapine, like other antidepressants can cause/worsen movement disorders:
https://www.drugs.com/mirtazapine.html
Mirtazapine Brand names: Remeron, Remeron SolTab Medically reviewed by Kaci Durbin, MD. Last updated Feb 3, 2022.
For the Consumer. Side effects include: Decreased or increased movement
For Healthcare Professionals Side effects include: Nervous system
Common (1% to 10%):, tremor
Uncommon (0.1% to 1%): hypokinesia, hyperkinesia,
Rare (0.01% to 0.1%): dyskinesia, extrapyramidal syndrome, dystonia, restless legs, akathisia (psychomotor restlessness)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605300/
Mirtazapine-associated movement disorders: A literature review Jamir Pitton Rissardo and Ana Leticia Fornari Caprara Tzu Chi Med J. 2020 Oct-Dec; 32(4): 318–330.
https://www.frontiersin.org/articles/10.3389/fneur.2017.00547/full
Intrajejunal Infusion of Levodopa-Carbidopa Gel Can Continuously Reduce the Severity of Dropped Head in Parkinson’s Disease H.Kataoka, Y.Sawada, T.Namizaki, N.Shimozato, H.Yoshiji and S.Ueno Front. Neurol., 16 October 2017 |
Doherty et al. mentioned that antecollis might be an off-state phenomenon or a dyskinesia-like phenomenon related to dopaminergic medications.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353458/pdf/MDC3-4-901.pdf
Anterocollis as an “Off” Phenomenon in Parkinson Disease Z.Guduru, J.Morgan, K.D.Sethi July 2017 Movement Disorders Clinical Practice 4(6)