Thank you for your responses. At the moment it seems unlikely that I will be prescribed opicapone before I have at least tried entacapone first to see if I can tolerate it. That appears to be the policy of my local NHS, even if not elsewhere.
However, I’m having difficulty contacting my neurologist at the moment to discuss the next step. This is understandable given the current crisis, but I am facing the possibility of not being able to get any new drugs (i.e. that I haven’t been prescribed before) for a few months.
This is not a happy situation for me, because I am not doing very well: worsening dystonia and a lot of very uncomfortable muscle stiffness plus movement difficulties and poor balance. I have marginally increased my levodopa intake and that is helping: I’m taking a slow release Madopar overnight, and allowing myself one 62.5 dispersible during the day, on top of the 5x125 Madopar that I’ve been taking for the last year or so.
I also think my symptoms, particularly the dystonia, may be exacerbated by stress. Apart from the covid 19 crisis, I’ve recently had a virus infection, an abscessed tooth and one of our pet cats died. I think one way I might lessen my symptoms is if I stop obsessively reading and watching the news!
If I can’t get to talk with my neuro this week, I’ll try to contact the PUK advice line. I’ve been reluctant to do that before now because I’m sure they are inundated with calls about corvid 19.