Sinemet shortage status


Just returned from the Chemist who said they are unable to fulfil my regular monthly prescription. They offered no advice as to what to do so I have asked the GP for some advice. I see from earlier posts that there were shortages in September and October. Does anyone know the current position? I react badly to changes so would be wary of a generic approach. I take Sinemet 12.5/50mg.


This is the most recent info I’m aware of. You could try ringing the helpline as they may have more information.


Thanks for sharing that link @Mountainair.

Hi @Marigold, Sinemet should be available as far as I know. Have you tried an alternative chemist? It may just be that that chemist had not ordered batch. Alternatively, you could ask you pharmacist to contact MSD to check about supply in your area. Please keep me posted on how you get on.

Best wishes,


I here certainly seems to be a problem in the Cambridge area. Lloyds chemist do not seem to know when deliveries to the UK might be made. Out local village branch was less than helpful: I was told to go back to the GP and get an alternative prescription (but no suggestion of what!). They did not return the original prescription so I had to go back to the GP to get a duplicate prescription so I could try other pharmacies before really panicking! I take 12.5/50 Sinemet - double dose rather than use 25/100 Sinemet - but was unable to find any 12/.5/50 but did have an option of finding the 25/100 tablet. Boots in Newmarket fortunately still had a box of 25/100 which they have reserved for me and I have to go back to the GP to pick up a revised 'script for the alternative tablet size. Boots had been told by MSD that there were delivery problems for the 12.5/50s for which there are no generic alternatives according to the web site. They were very helpful. I pick up the revised script from the GP this morning and will go back to Boots - fingers crossed the reserved box is still available. I do not really want to change drug regime which would appear to be the backstop.
Being told there were no tablets available at my original chemists was like suddenly standing on the edge of an abyss. It has made me feel really vulnerable.


Hi @Marigold,

What a fiasco - I hope you were able to get the box of 25/100 at Boots. It’s a shame that you had to get another prescription but I also hope it didn’t inconvenience you too much. If you need any more support on this, please do not hesitate to contact our helpline on 0808 800 0303.

Best wishes,


Can anybody tell how expensive sinemet is. I live in Illinois . I have

several samples. But was wondering about the cost.


I’ve been taking Sinemet since November last year and am on !0mg/100mg three times a day. My local chemist has been unable to provide Sinemet for my last two prescriptions and has given me a generic alternative Co-careldopa. I can see from previous posts that shortages aren’t unusual. Do we know why? Has anyone found a solution? Has anyone had experience of using the generic alternatives? Thanks in advance for any responses.


Hi @Mari,

I just wanted to chime in here to let you know that we’ve got info on the supply issue coming out later this week which I’ll keep the forum posted on.



I am due to start on Sinemet 12.5/50mg and was due to collect them today, but got a call to say that the wholesaler can’t get them till mid-June. She is going to call my GP on Monday to let her know and seek guidance. I guess waiting isn’t a disaster - I haven’t started on the meds yet so can wait I think.



Have just come back from my local pharmacy who have advised that they can’t fulfil my prescription due to a lack of supplies at the warehouse. They are going to get back to me later this week and then see if there are any generics available. I take 2x12.5/50mg 5 times day so could replace with 25/100mg if necessary. I just hope it is not as chaotic as last time!